Endotoxin is the major cell wall component of Gram-negative bacteria. It is a major contaminant found in biologically active substances. Endotoxin detection test is one of the most critical quality control tests required by the FDA for all drugs in their final formulation. In vitro, it can introduce a bias in experiments involving cells sensitive to LPS. Therefore, it is crucial to remove endotoxin from human and animal parenteral drugs, biological products, and medical devices.


Who Upvoted this Story